Long-term HRV analysis shows stress reduction by magnesium intake
MMW Fortschr Med. 2016 Dec;158(Suppl 6):12-16. Epub 2016 Dec 8.
Wienecke E, et al.
Mental pressure and stress represent an ever-increasing socio-political
challenge. The heart rate variability (HRV) measurement, which has its
origin in the cardiac function diagnosis, gives information on the
neurovegetative activity. A low HRV shows an imbalance of the
sympathetic and parasympathetic efferents and thus is an indicator of
randomized, controlled, two-armed parallel study with 100 participants
and a period of 90 days was performed. Main object of investigation was
to what extent the mineral magnesium, which is also a high-quality
natural calcium antagonist in cardiology, can influence the
sympathovagal balance, when given in combination with a
strength-endurance training. The effect on intracellular magnesium
concentration was investigated as an additional parameter.
RESULTS: In the
group with daily supplementation of 400 mg of magnesium, HRV parameters
clearly increased: pNN50 - an indicator of parasympathetic activity -
increased. LF-HF ratio as well as stress index - low values for each
represent a good balance of the vegetative nervous system - decreased.
In the control group no positive changes in HRV parameters could be
shown. Vagus activity, and thus the adaptive and regenerative capacity
of the body, veritably increased by magnesium supplementation. No effect
on the intracellular magnesium concentration could be shown in the
results of this study point out that persons with mental and physical
stress can benefit from a daily intake of magnesium. This might lead to
an improved physiological regulation of the sympathetic and
parasympathetic efferents and, furthermore, prevent magnesium deficiency
and diseases such as, for example, restlessness, irritability, lack of
concentration, sleep disorder or depression.
of Evidence Linking Calcium With or Without Vitamin D Supplementation
to Cardiovascular Disease in Generally Healthy Adults: A Clinical
Guideline From the National Osteoporosis Foundation and the American
Society for Preventive Cardiology
Ann Intern Med. 2016 Dec 20;165(12):867-868. doi: 10.7326/M16-1743. Epub 2016 Oct 25.
Kopecky SL, et al.
Calcium is the dominant mineral present in bone and a shortfall nutrient
in the American diet. Supplements have been recommended for persons who
do not consume adequate calcium from their diet as a standard strategy
for the prevention of osteoporosis and related fractures. Whether
calcium with or without vitamin D supplementation is beneficial or
detrimental to vascular health is not known.
The National Osteoporosis Foundation and American Society for
Preventive Cardiology convened an expert panel to evaluate the effects
of dietary and supplemental calcium on cardiovascular disease based on
the existing peer-reviewed scientific literature. The panel considered
the findings of the accompanying updated evidence report provided by an
independent evidence review team at Tufts University.
The National Osteoporosis Foundation and American Society for Preventive
Cardiology adopt the position that there is moderate-quality evidence
(B level) that calcium with or without vitamin D intake from food or
supplements has no relationship (beneficial or harmful) to the risk for
cardiovascular and cerebrovascular disease, mortality, or all-cause
mortality in generally healthy adults at this time. In light of the
evidence available to date, calcium intake from food and supplements
that does not exceed the tolerable upper level of intake (defined by the
National Academy of Medicine as 2000 to 2500 mg/d) should be considered
safe from a cardiovascular standpoint.
of magnesium, probiotic, and vitamin food supplementation in healthy
subjects with psychological stress and evaluation of a persistent effect
after discontinuing intake
Panminerva Med. 2016 Dec;58(4):263-270. Epub 2016 Jun 16.
Allaert FA, et al.
(AA) BACKGROUND: The
aim of this paper was to describe the changes in subjects' psychological
stress intensity under the effect of dietary supplements of magnesium,
probiotics, and vitamins after one month of intake.
METHODS: Observational cohort study of subject complaining of
psychological stress defined by a Perceived Stress Scale (PSS 10) score
of more than 21.
RESULTS: The study covered 242
healthy volunteers, 38.6±13.6-year-old, among whom 79.8% were women.
Under the effect of the supplementation of magnesium, probiotics, and
vitamins, the psychological stress of the subjects decreased
significantly from 34.1±4.5 to 26.2±6.1 (P<0.0001), which corresponds
to an average reduction of 22.7±16.0%. Fatigue decreased even more
significantly from 16.8±6.4 to 8.7±6.2 (P<0.0001), which corresponds
to an average reduction of 45.0%±38.1%. Analysis showed that the
psychological stress level was strictly similar one month after the
treatment was discontinued and therefore clearly demonstrated that the
psychological benefit was maintained over time.
Stress and fatigue are significantly reduced by the intake of a food
supplement with probiotics, magnesium, vitamins, and minerals and this
effect is fully maintained one month after discontinuing the food
Gluten free diet and nutrient deficiencies: A review
Clin Nutr. 2016 Dec;35(6):1236-1241. doi: 10.1016/j.clnu.2016.05.002. Epub 2016 May 7.
Vici G, et al.
(AA) BACKGROUND & AIMS:
The only available treatment for celiac disease (CD) is lifelong
adherence to gluten free (GF)-diet. However, GF-diet may lead to
possible nutrient unbalance resulting in improper nutritional quality of
diet. The aim of this study is to evaluate the nutritional quality of
METHODS: MEDLINE®/PubMed and Cochrane Library were electronically searched for articles published between 1990/01/01 and 2015/09/01.
GF-diet was found to be poor in alimentary fiber due in particular to
the necessary avoidance of several kinds of foods naturally rich in
fiber (i.e. grain) and the low content of fiber of GF product that are
usually made with starches and/or refined flours. Micronutrients are
also found to be poor, in particular Vit. D, Vit. B12 and folate, in
addition to some minerals such as iron, zinc, magnesium and calcium.
Moreover, an inadequate macronutrient intake was reported related above
all to the focus on the avoidance of gluten that often leaving back the
importance of nutritional quality of the choice. In particular, it was
found a higher content of both saturated and hydrogenated fatty acids
and an increase in the glycemic index and glycemic load of the meal.
Despite the GF-diet is necessary in celiac disease treatment and the
attention is on gluten avoidance, the evaluation of nutritional quality
of the diet must be considered. Moreover, educational strategies based
on the relationship between nutrients and food and human health could be
developed to optimize the therapeutic approach in celiac patients.